Macrocyclic urea derivatives as inhibitors of TAFIa, their preparation and their use as pharmaceuticals

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专利权人:

Sanofi

发明人:

Evers, Andreas,Kallus, Christopher,Wagner, Michael,Wehlan, Hermut

申请号：

AU2014280329

公开号：

AU2014280329A1

申请日:

2014.06.05

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present invention relates to macrocydic urea derivatives of the formula I (I) in which R1, R2, R3, V and Y are as defined below. The compounds of the formula I are inhibitors of the enzyme TAFIa (activated thrombin-activatable fibrinolysis inhibitor). The invention further relates to the process for the preparation of the compounds of formula I and to the use thereof as medicaments.

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