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DERIVES DE DIHYDROPYRIDINONE
专利权人:
BAYER HEALTHCARE AG
发明人:
GIELEN-HAERTWIG, HEIKE,ALBRECHT, BARBARA,BAUSER, MARCUS,KELDENICH, JOERG,LI, VOLKHART,PERNERSTORFER, JOSEF,SCHLEMMER, KARL-HEINZ,TELAN, LEILA
申请号:
CA2556463
公开号:
CA2556463C
申请日:
2005.02.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to novel dihydropyridinone derivatives, processesfor their preparation, and their use in medicaments, especially for thetreatment ofchronic obstructive pulmonary diseases, acute coronary syndrome, acutemyocardialinfarction and heart failure development.In a specific embodiment, the invention relates to a compound of thegeneral formula (I)(see formula I)or a salt, hydrate and/or solvate thereof, or a tautomeric form thereof,whereinR1 and R3 independently from each other represent hydrogen, halogen,nitro, etc.,R6 represents- a group of the formula(see formula II)which can be substituted by up to two radicals independently selected from thegroupconsisting of C1-C6-alkyl, C1-C6-alkoxy, hydroxycarbonyl, etc.,- a group of the formula(see formula III) or (see formula IV)which are substituted by one or two radicals independently selected from thegroupconsisting of C1-C6-alkyl, hydroxy, C1-C6-alkoxy,etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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