您的位置: 首页 > 农业专利 > 详情页

COMPOSES DE TYPE TAXANES, LEUR PROCEDE DE PREPARATION ET LEURS UTILISATION
专利权人:
LTD.;JIANGSU TASLY DIYI PHARMACEUTICAL CO.
发明人:
ZHOU, WEI,JING, YUNRONG,WANG, YONGFENG,WANG, GUOCHENG
申请号:
CA2931291
公开号:
CA2931291A1
申请日:
2014.11.21
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention provides taxanes compounds with a formula (I) or formula (II) structure, a method for preparing the compounds, and the compound, and uses of medicinal salts thereof and solvates used as compositions of active ingredients in the preparation of oral antitumor medicaments. In formula (I), R1 is -COR6, -COOR6, or -CONR7aR7b; R2 is C1-C6 alkyl, C1-C6 alkenyl, substitution hydrocarbyl, heterocyclic radical, aromatic group or substitute aromatic nucleus; R3 is -OR6, -OCOOR6, -OCOSR6, or -OCONR7aR7b; R4 is -OR6, -OCOOR6, -OCOSR6, -OCONR7aR7b, or H; R6 is C1-C6 alkyl, C1-C6 alkenyl, C1-C6 alkynyl, substitution hydrocarbyl, aromatic group or heterocyclic radical; R7a, R7b is hydrogen, hydrocarbyl, substitution hydrocarbyl or heterocyclic radical. In formula (II), R1 is -COR6, or -COOR6; R2 is aromatic group; R3 is -OR6; and R6 is C1-C6 alkyl, C1-C6 alkenyl, C1-C6 alkynyl, substitution hydrocarbyl, aromatic group or heterocyclic radical.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充