BARBÉ GARCIA, JORGE,BADIOLA, SÁIZ,LLAGOSTERA CASAS, MONTSERRAT,GARRIDO OCAÑA, MA ELENA,BOSCH GALLEGO, MONTSERRAT,PEREZ DE ROZAS RUIZ DE GAUNA, ANA MA
申请号:
DK09705071
公开号:
DK2256185T3
申请日:
2009.01.29
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
The invention relates to Pasteurella multocida mutants capable of providing heterologous protection against infection caused by virulent P . multocida. Said mutants are defective in fur ampH and fur ompH galE genes. The invention relates to Pasteurella multocida bacteria vaccine compositions containing fur ompH double mutants and fur ompH galE triple mutants obtained from P . multocida , or an extract of iron-regulated outer-membrane proteins (IROMPs) obtained from said mutants, and to an excipient and/or pharmaceutically acceptable adjuvants.