JORGE BARBÉ GARCIA,SÁIZ BADIOLA,MONTSERRAT LLAGOSTERA CASAS,MA ELENA GARRIDO OCAÑA,MONTSERRAT BOSCH GALLEGO,ANA MA PEREZ DE ROZAS RUIZ DE GAUNA
申请号:
PT09705071
公开号:
PT2256185E
申请日:
2009.01.29
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
The invention relates to Pasteurella multocida mutants capable of providing heterologous protection against infection caused by virulent P . multocida. Said mutants are defective in fur ampH and fur ompH galE genes. The invention relates to Pasteurella multocida bacteria vaccine compositions containing fur ompH double mutants and fur ompH galE triple mutants obtained from P . multocida , or an extract of iron-regulated outer-membrane proteins (IROMPs) obtained from said mutants, and to an excipient and/or pharmaceutically acceptable adjuvants.