Genisphere, LLC;Lankenau Institute of Medical Research
发明人:
Robert C. Getts,James Kadushin,Mindy George-Weinstein,Jacquelyn Gerhart,Emanuela Dylgjeri,Kelly Rhodes
申请号：
US16568702
公开号：
US20200148763A1
申请日:
2019.09.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Compositions and methods for targeted delivery of active agents to cells are provided. The compositions comprise a wholly or partially double-stranded synthetic DNA carrier, and an active agent intercalated in double-stranded portions of the DNA carrier. The DNA carrier may also be linked to a targeting agent. The compositions are useful for delivering an active agent into a targeted cell type, for example a cytotoxic agent.
