Charles Zepp,Yun Gao,Mark J. Keegan,Sam Baldwin,Fen-ni Fu,Lloyd Johnston,Grayson B. Lipford
申请号：
US13948129
公开号：
US20140030344A1
申请日:
2013.07.22
申请国别(地区):
US
年份:
2014
代理人:
摘要：
This invention relates to compositions, and related methods, of synthetic nanocarriers that target sites of action in cells, such as antigen presenting cells (APCs), and comprise immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner. Also disclosed are compositions and methods relating to synthetic nanocarriers that encapsulate labile immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner.
