Zepp, Charles,Gao, Yun,Keegan, Mark J.,Baldwin, Sam,Fu, Fen-Ni,Johnston, Lloyd,Lipford, Grayson B.
申请号:
AU2010254550
公开号:
AU2010254550B2
申请日:
2010.05.26
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
This invention relates to compositions, and related methods, of synthetic nanocarriers that target sites of action in cells, such as antigen presenting cells (APCs), and comprise immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner. Also disclosed are compositions and methods relating to synthetic nanocarriers that encapsulate labile immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner.