The invention relates to an apparatus for desynchronization of neural, illness-synchronous brain activity in which, according to the invention, the activities in at least two subareas of a brain area or at least two functionally associated brain areas are stimulated by means of at least two electrodes, on the basis of which, in the case of a person with an illness, desynchronization surprisingly occurs in the relevant neuron population and the symptoms are suppressed. The feedback stimulation signal, that is to say the measured, time-delayed and process neural activity, is used as an individual stimulus. In consequence, this results in demand control, which is self-regulating according to the invention, of the amplitude of the stimulation signal thus minimizing the intensity of the stimulation stimuli automatically after successful desynchronization. For successful operation, the apparatus requires neither complex calibration nor control of the stimulation parameters and, instead, these can preferably be adapted and optimized by the additional controller. The apparatus has at least two stimulation electrodes (2) and at least one sensor (3), which are driven by a controller such that they result in desynchronization in their local environment.