A device for desynchronizing neuronal brain activity involving a neuron population firing in a synchronized manner at a pathological frequency. The device includes an electrode configured to generate stimuli that stimulate the neuron population； and a control unit configured to control the electrode to generate the stimuli in sequence, wherein the stimuli succeed each other with a predetermined frequency f. The predetermined frequency f is substantially equal to g×n/m, where g is the pathological frequency, and n and m are integers.
