KRIEG, ARTHUR, M.,SUBRAMANIAN, ROMESH,MCSWIGGEN, JAMES,LEE, JEANNIE, T.
申请号：
EP13791343
公开号：
EP2850189A4
申请日:
2013.05.16
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Aspects of the invention provide methods for selecting a candidate oligonucleotide for activating expression of a target gene. Further aspects of the invention provide methods of selecting a set of oligonucleotides that is enriched in oligonucleotides that activate expression of a target gene. Further aspects provide single stranded oligonucleotides that modulate gene expression and compositions and kits comprising the same. Methods for modulating gene expression using the single stranded oligonucleotides are also provided.
