A supplement composition for supporting telomere maintenance and protection, including effective amounts of extract of silybum marianum N-acetylcysteine Resveratrol Extract of Panax ginseng Extract of Ginkgo biloba Puerarin and L-arginine.Further disclosed is a method for supporting telomere maintenance and protection, comprising orally administering a supplement composition to a person one or twice daily, said supplement composition comprising in one dosage: from about 100 mg to about 300 mg of extract of silybum marianum, from about 400 mg to about 600 mg of N-acetylcysteine, from about 40 mg to about 60 mg of trans-resveratrol, from about 80 mg to about 120 mg of extract of Panax ginseng, from about 40 mg to about 60 mg of extract of ginkgo biloba, and from about 80 mg to about 120 mg of puerarin, and from about 400 mg to about 600 mg of L-arginine.