BEE, JARED J,SANTACROCE, PAUL P,DU, JIALI J,DIMITROVA, MARIANA M,‧比,‧桑塔克羅斯,‧杜,‧季米特洛娃
申请号:
HK15112690.1
公开号:
HK1211840A
申请日:
2015.12.24
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL6 antibody. In some embodiments, the invention is directed to a stable, low viscosity antibody formulation comprising about 50 mg/mL to about 400 mg/mL of an anti-IL6 antibody, and arginine, wherein the antibody formulation is in an aqueous solution and has a viscosity of less than 20 cP at 23° C. Also provided are methods of making and methods of using such antibody formulations.