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PEPTIDIC COMPOUND AND USE OF SAME
专利权人:
KEIO UNIVERSITY
发明人:
SUENAGA, KIYOTAKE,TERUYA, TOSHIAKI,SASAKI, HIROAKI
申请号:
EP10804358
公开号:
EP2460814A4
申请日:
2010.07.26
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
An object of the present invention is to provide a novel compound having an antitumor/anticancer effect. Specifically, the present invention provides a compound represented by Formula (I), a derivative thereof or a salt of the same. In Formula (I), R1 represents an alkyl group, an alkenyl group, a cycloalkyl group, an amino group, a monoalkylamino group, a dialkylamino group, an aryl group, a heteroaryl group, an aralkyl group or an alkoxy group R2 represents a substituted or unsubstituted amino group or a substituted or unsubstituted nitrogen-containing heterocyclic group and R3 represents hydrogen, halogen, alkyl, methoxy, cyano, trifluoromethyl, acetylamino or amino. In Formula (I), N-Me-Ala may be substituted with N-Me-Gly, N-Me-Ser, N-Me-Thr, Ala, Gly, Ser or Thr N-Me-Phe may be substituted with Phe, Tyr or N-Me-Tyr and D-Leu may be substituted with L-Leu.
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