DEPIGMENTING PHARMACEUTICAL COMPOSITION COMPRISING N- (2 - ((3- (4-BROMOPHENYL) -2-PROPENYL) AMINO) ETHYL) -5-ISOQUINOLINESULFONAMIDE (H89)

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专利权人:

GALDERMA RESEARCH & DEVELOPMENT;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE INSERM

发明人:

CORINE BERTOLOTTO,ROBERT BALLOTTI,FLAVIE LUCIANI,MEHDI KHALED

申请号：

FR0511977

公开号：

FR2893841B1

申请日:

2005.11.25

申请国别(地区):

FR

年份:

2014

代理人:

摘要：

Use of N-(2-((3-(4-bromophenyl)-2-propenyl)amino)ethyl)-5-isoquinolinesulfonamide (I) to prepare a medicament for the treatment of hyperpigmentary disorders. ACTIVITY : Cytostatic； Dermatological. MECHANISM OF ACTION : Tyrosine kinase inhibitor. The tyrosine kinase inhibiting activity of (I) was tested. The result showed that (I) had a percentage activation of 120.

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