DHAR T G MURALI,DUAN JINGWU,GONG HUA,JIANG BIN,LU ZHONGHUI,WEINSTEIN DAVID S
申请号：
IN201617011637
公开号：
IN201617011637A
申请日:
2016.04.01
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Described are RORy modulators of the formula (I) or pharmaceutically acceptable salts thereof wherein all substituents are defined herein. The invention includes stereoisomeric forms of the compounds of formula I including stereoisomerically pure scalemic and racemic form as well as tautomers thereof. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORy activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORy activity for example autoimmune and/or inflammatory disorders.
