Mackenzie, Lloyd F.,Macrury, Thomas B.,Harwig, Curtis,Bogucki, David,Raymond, Jeffery R.,Pettigrew, Jeremy D.,Khlebnikov, Vladimir,Shan, Rudong
申请号：
AU2018220093
公开号：
AU2018220093A1
申请日:
2018.08.23
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018220093A120180913.pdf#####ABSTRACT Compounds of formula (1): R1 R4a 83 R4 b (I R5 R 7 A where , n, R1, R4 ", R4b, R , R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising a compound of formula (1) in combination with a pharmaceutically acceptable carrier or diluent are also disclosed, as are methods of SHIP1 modulation by administration of such compounds to an animal in need thereof. 97Q
