John E. PARK,Cornelia DORNER-CIOSSEK,Stefan HOERER,Lothar KUSSMAUL,Martin LENTER,Katharina ZIMMERMANN,Gerald BESTE,Toon LAEREMANS,Pascal MERCHIERS,Jo VERCAMMEN
申请号：
US13617248
公开号：
US20130017209A1
申请日:
2012.09.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to biparatopic A-beta binding polypeptides and, more specifically, to biparatopic A-beta binding polypeptides comprising at least two immunoglobulin single variable domains binding to different epitopes of A-beta. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as Alzheimer's Disease.
