Park, John E.,Dorner-Ciossek, Cornelia,Hoerer, Stefan,Kussmaul, Lothar,Lenter, Martin,Zimmermann, Katharina,Beste, Gerald,Laeremans, Toon,Merchiers, Pascal,Vercammen, Jo
申请号:
AU2011222980
公开号:
AU2011222980B2
申请日:
2011.03.02
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The invention relates to biparatopic A-beta binding polypeptides and, more specifically, to biparatopic A-beta binding polypeptides comprising at least two immunoglobulin single variable domains binding to different epitopes of A-beta. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as Alzheimer's Disease.