PARK, JOHN, E.,DORNER-CIOSSEK, CORNELIA,HOERER, STEFAN,KUSSMAUL, LOTHAR,LENTER, MARTIN,ZIMMERMANN, KATHARINA,BESTE, GERALD,LAEREMANS, TOON,MERCHIERS, PASCAL,VERCAMMEN, JO
申请号:
SG2012061024
公开号:
SG183369A1
申请日:
2011.03.02
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
The invention relates to biparatopic A-beta binding polypeptides and, more specifically, to biparatopic A-beta binding polypeptides comprising at least two immunoglobulin single variable domains binding to different epitopes of A-beta. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as Alzheimer's Disease.