John E. Park,Cornelia Dorner-Ciossek,Stefan Hoerer,Lothar Kussmaul,Martin Lenter,Katharina Zimmerman,Gerald Beste,Toon Laeremans,Pascal Gerard Merchiers,Jo Vercammen
申请号：
US14013364
公开号：
US09211330B2
申请日:
2013.08.29
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention relates to biparatopic A-beta binding polypeptides and, more specifically, to biparatopic A-beta binding polypeptides comprising at least two immunoglobulin single variable domains binding to different epitopes of A-beta. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as Alzheimer's Disease.
