Antonin De Fougerolles,John Diener,Emma Hickman,Gregory Hinkle,Stuart Milstein,Anne-Marie Pulichino,Andrew Griffin Sprague
申请号:
US15166576
公开号:
US09752152B2
申请日:
2016.05.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure relates to RNAi agents useful in methods of treating BetaENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.