Antonin De Fougerolles,John Louis Diener,Emma Hickman,Gregory Hinkle,Stuart Milstein,Anne-Marie Pulichino,Andrew Griffin Sprague
申请号:
US14723555
公开号:
US09376683B2
申请日:
2015.05.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure relates to RNAi agents useful in methods of treating BetaENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.