De Fougerolles, Antonin,Diener, John L.,Hickman, Emma,Hinkle, Gregory,Milstein, Stuart,Pulichino, Anne-Marie,Sprague, Andrew
申请号:
AU2011244335
公开号:
AU2011244335B2
申请日:
2011.04.20
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.