CYTOKINETICS, INC.;GLOBAL BLOOD THERAPEUTICS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
METCALF, BRIAN,CHUANG, CHIHYUAN,WARRINGTON, JEFFREY,JACOBSON, MATTHEW P.
申请号：
CA2860323
公开号：
CA2860323A1
申请日:
2012.12.28
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
