CYTOKINETICS, INC.; INC.;GLOBAL BLOOD THERAPEUTICS, INC.;GLOBAL BLOOD THERAPEUTICS;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
METCALF, BRIAN,CHUANG, CHIHYUAN,WARRINGTON, JEFFREY,PAULVANNAN, KUMAR,JACOBSON, MATTHEW P.,HUA, LAN,MORGAN, BRADLEY
申请号：
EP12862525
公开号：
EP2797416A4
申请日:
2012.12.28
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Provided are substituted benzaldehydes and derivatives thereof of formula (I) that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
