Kyriacos C. NICOLAOU,Ruofan LI,Zhaoyong LU,Te-ik SOHN,James WOODS,Emmanouil N. PITSINOS
申请号：
US15740656
公开号：
US20180327439A1
申请日:
2016.06.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
In one aspect, the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, antibody drug conjugates of the compounds are also provided.
