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Total synthesis of shishijimicin A and analogs thereof
专利权人:
William Marsh Rice University
发明人:
Nicolaou, Kyriacos C.,Li, Ruotan,Lu, Zhaoyong,Sohn, Te-Ik,Woods, James,Pitsinos, Emmanouil N.
申请号:
AU2016286071
公开号:
AU2016286071A1
申请日:
2016.06.29
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
In one aspect, the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, antibody drug conjugates of the compounds are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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