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TOTAL SYNTHESIS OF SHISHIJIMICIN A AND ANALOGS THEREOF
专利权人:
发明人:
NICOLAOU KYRIACOS C,LI RUOFAN,LU ZHAOYONG,SOHN TE IK,WOODS JAMES,PITSINOS EMMANOUIL N
申请号:
IN201817003072
公开号:
IN201817003072A
申请日:
2018.01.25
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
In one aspect the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally antibody drug conjugates of the compounds are also provided.
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