COMPOSES HETEROAROMATIQUES FUSIONNES SUBSTITUES COMME INHIBITEUR DE LA KINASE ET LEUR UTILISATION

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专利权人:

IMPACT THERAPEUTICS; INC

发明人:

CAI, SUIXIONG,TIAN, YE EDWARD

申请号：

CA3049608

公开号：

CA3049608A1

申请日:

2018.01.09

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention provides a substituted fused heteroaryl compound serving as a kinase inhibitor, and applications thereof. Specifically, the present invention provides a compound represented by formula I, or a medicinal salt or a prodrug thereof, A1-A4, B1-B3, D1-D4 and R1-R3 being defined herein. The compound represented by formula I is a kinase inhibitor. Accordingly, the compound in the present invention can be used for treating cancer and other clinical conditions caused by a defect in a DDR function.

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