A preventive or ameliorating agent for age-related cognitive dysfunction, a neurotrophin 3 enhancer, a preventive or ameliorating agent for age-related decline in motivation, and a method for producing these.
PROBLEM TO BE SOLVED: To provide an agent for preventing or ameliorating cognitive dysfunction associated with aging and an agent for enhancing neurotrophin 3. A tea leaf or an agent for preventing or ameliorating cognitive dysfunction associated with aging, which comprises a tea leaf or a tea leaf extract which is an extract of the tea leaf, wherein the tea leaf and the tea leaf extract are non-gallate type catechin and theogallin. The ratio of theogallin molar concentration (μmol / L) to the molar concentration of non-gallate catechin (μmol / L) is 0.3 or more, a preventive or ameliorating agent for cognitive dysfunction associated with aging, and , A tea leaf or a tea leaf extract which is an extract of the tea leaf, which is a enhancer of neurotrophin 3, wherein the tea leaf and the tea leaf extract contain non-gallate type catechin and theogallin, and the non-gallate type catechin. A neurotrophin 3 enhancer in which the ratio of theogallin molar concentration (μmol / L) to molar concentration (μmol / L) is 0.3 or more. [Selection diagram] Fig. 3【課題】加齢に伴う認知機能障害の予防又は改善剤、及び、ニューロトロフィン３の増強剤を提供すること。【解決手段】茶葉又は該茶葉の抽出物である茶葉抽出物を含む、加齢に伴う認知機能障害の予防又は改善剤であって、前記茶葉及び前記茶葉抽出物は、非ガレート型カテキン及びテオガリンを含み、非ガレート型カテキンのモル濃度（μｍｏｌ／Ｌ）に対するテオガリンのモル濃度（μｍｏｌ／Ｌ）の割合が、０．３以上である、加齢に伴う認知機能障害の予防又は改善剤、及び、茶葉又は該茶葉の抽出物である茶葉抽出物を含む、ニューロトロフィン３の増強剤であって、前記茶葉及び前記茶葉抽出物は、非ガレート型カテキン及びテオガリンを含み、非ガレート型カテキンのモル濃度（μｍｏｌ／Ｌ）に対するテオガリンのモル濃度（μｍｏｌ／Ｌ）の割合が、０．３以上である、ニューロトロフィン３の増強剤。【選択図】図３
