AMERICKS, Michael K.,RECH, Jason C.,SAVALL, Brad M.,WALL, Jessica L.
申请号：
ES14722872
公开号：
ES2689526T3
申请日:
2014.03.14
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
A compound of Formula I ** Formula ** wherein: each R2 is independently selected from the group consisting of H, halo, SO2CH3, C1-C3 alkyl, NO2, NH2, perhaloalkyl and perhaloalkoxy； or two R2 substituents are taken together to form: ** Formula ** n is 0-3； X is H or C1-C3 alkyl； Y is independently selected from the group consisting of H, C1-C3 alkyl and C3-C4 cycloalkyl； R1 is independently selected from the group consisting of: ** Formula ** Ra, Rc and Rg are independently H or halo； Rd is H or C1-C3 alkoxy； Re is independently selected from the group consisting of H, C1-C3 alkyl and halo； Rb, Rf, Rh, Ri, Rj, Rk, Rl, Rm, Rn, Ro are independently selected from the group consisting of H, C1-C3 alkyl and perhaloalkyl； and Rp is H or C (O) OtBu； or a pharmaceutically acceptable salt of a compound of Formula (I).Un compuesto de Fórmula I**Fórmula** en donde: cada R2 se selecciona independientemente del grupo que consiste en H, halo, SO2CH3, C1-C3 alquilo, NO2, NH2, perhaloalquilo y perhaloalcoxi； o dos sustituyentes R2 se toman juntos para formar:**Fórmula** n es 0-3； X es H o C1-C3 alquilo； Y se selecciona independientemente del grupo que consiste en H, C1-C3 alquilo y C3-C4 cicloalquilo； R1 se selecciona independientemente del grupo que consiste en:**Fórmula** Ra, Rc y Rg son independientemente H o halo； Rd es H o C1-C3 alcoxi； Re se selecciona independientemente del grupo que consiste en H, C1-C3 alquilo y halo； Rb, Rf, Rh, Ri, Rj, Rk, Rl, Rm, Rn, Ro se seleccionan independientemente del grupo que consiste de H, C1-C3 alquilo y perhaloalquilo； y Rp es H o C(O)OtBu； o una sal farmacéuticamente aceptable de un compuesto de Fórmula (I).
