MCCARRON ASHLEY SUE,SELLS TODD B,STIRLING MATTHEW,STROUD STEPHEN G
申请号：
IN1936/DELNP/2014
公开号：
IN2014DN01936A
申请日:
2014.03.13
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Disclosed are chemical entities which are inhibitors of Nedd8 activating enzyme (NAE) namely the compound {(1S 2S 4R) 4 [(6 {[(1R 2S) 5 chloro 2 methoxy 2 3 dihydro 1H inden 1 yl]amino}pyrimidin 4 yl)oxy] 2 hydroxycyciopentyl}methyl sulfamate and pharmaceutically acceptable salts thereof solid state forms thereof and prodrugs thereof. Also disclosed are methods of using the chemical entities to treat disorders such as cancer.
