SHIAO, YOUNG JI,萧永基,蕭永基,CHEN, CHIN CHU,陈劲初,陳勁初,LEE, LI YA,李丽雅,李麗雅,CHEN, WAN PING,陈婉屏,陳婉屏
申请号：
TW104141897
公开号：
TW201720453A
申请日:
2015.12.14
申请国别(地区):
TW
年份:
2017
代理人:
摘要：
The present invention provides an active substance for treating dementia, a preparation method thereof, a pharmaceutical composition containing the same, and a preparation method of the pharmaceutical composition. The preparation method of the active substance is prepared through manners of plate culture, flask culture and fermentation tank culture to obtain active substance of mycelium of Hericium erinaceus in powdery form. The mycelium powder of Hericium erinaceus can be further extracted with alcohol solvent to obtain alcohol extract, which is further purified and separated to obtain erinacines A and S.本發明提供一種治療失智症之活性物質、其製備方法、含其之醫藥組合物、及該醫藥組合物的製備方法。該活性物質之製備方法係透過平板培養、燒瓶培養、醱酵槽培養之方式製備，而得到粉末型態的猴頭菇菌絲體活性物質。該猴頭菇菌絲體粉末可進一步以醇類溶劑進行萃取獲得醇萃物，再進一步純化分離，獲得一猴頭素A與S。
