1. Requirement 1: a compound (1) with formula characteristics,X is nr8308o； R1 is a single ring or double ring heteromorphic group, in which R1 is not replaced or replaced by one or more substitutes independently selected from asphalt, halogen, halide, halide, oh-o-asphalt, cn-nr7491； r74955；-N (Rᵃ) C (O) alkyl, -N (Rᵃ) CO₂-alkyl, -N (Rᵃ) SO₂-alkyl, -C (O) alkyl, -CO₂H, -CO₂-alkyl, -CONRᵃRᵇ,-So8322 asphalt, y-so8322； nr7491； r74955；R749191 and r74955 are independent h or tar； R2 is phenyl or monocyclic heterogeneity, in which R2 is not replaced or replaced by one or more substitutes selected independently from a group of asphalt, halogen, cyclopropylsulfonyl, haloacyl fluoride, oh-o-asphalt, cn-nr75808； r74966；-N (Rᵃ) C (O) alkyl, -N (Rᶜ) CO₂-alkyl, -N (Rᶜ) SO₂-alkyl, -C (O) alkyl, -CO₂H, -CO₂-alkyl, -CONRᶜRᵈ,-So8322 asphalt, y-so8322； nr7580； r74966；R758080 and r74966 are independent h or tar； R3 is phenyl or monocyclic isomer, wherein R3 is not replaced, or replaced by one or more independent substitutes composed of asphalt, halogenated tar, halogenated Oh or asphalt-cn-nr7497； (r75844)；-N (r74977) C (o) lessor, - n (r74977) co832222 lessor, - n (r74977) so8322 lessor, - C (o) lessor, - co83222； - coi83222 lessor, - conr7497； - r75844；-So8322 asphalt, y-so8322； nr7497； r75844；Among them, r74977 and r75844 are independent h or rented； r8308s is h or rented； or a salt acceptable for drugs；Reivindicación 1: Un compuesto caracterizado porque es de fórmula (1), donde X es NR⁴ ó O； R¹ es un grupo heteroarilo monocíclico o bicíclico, donde R¹ no está sustituido o está sustituido con uno o más sustituyentes seleccionados en forma independiente entre el grupo que consiste en alquilo, haloalquilo, halo, -OH, -O-alquilo, -CN, -NRᵃRᵇ, -N(Rᵃ)C(O)alquilo, -N(Rᵃ)CO₂-alquilo, -N(Rᵃ)SO₂-alquilo, -C(O)alquilo, -CO₂H, -CO₂-alquilo, -CONRᵃRᵇ, -SO₂-alquilo, y -SO₂NRᵃRᵇ； donde Rᵃ y Rᵇ son en forma independiente entre sí H o alquilo； R² es fenilo o un heteroarilo monocíclico, donde R² n
