A stent is described that releases medicamentuous composition to prevent and treat restenosis and the fabrication process that comprehends between 10.0 to 500.0 Ug/cm2 of the surface of the stent coated with rapamicyn (sirolismus) or analogous and between 0.01 to 20.0 Ug/mm2 of the surface of the stent coated with paclitaxel or analogous.