PURPOSE: A composition containing Cannabis sativa extract for preventing or treating dental caries is provided to ensure excellent antibacterial effect and suppress glucosyltransferase activity. CONSTITUTION: A composition for preventing or treating dental caries contains 0.01-50 wt% of Cannabis sativa extract as an active ingredient. The extract is prepared using an extraction solvent such as water or an organic solvent. The inorganic solvent is alcohol of C1-C4, acetone, or a solution thereof. An oral composition is a toothpaste, oral cleanser, or oral spray. A health functional food for preventing or treating dental caries contains the extract as an active ingredient. The health food is a food or beverage. [Reference numerals] (AA) Cannabis sativa