A system for affecting a temperature of a patient, the system includes: a nose catheter that is adapted to be inserted into a nose upper channel and to receive a fluid and a temperature control and fluid supply unit that is adapted to supply the fluid and control a temperature of the fluid so as to affect a temperature of a brain of a patient when the nose catheter is inserted into the nose upper channel of a patient and receives the first fluid wherein the temperature control and fluid supply unit comprises: a thermoelectric heat pump that is arranged to transfer heat from a cold side to a hot side a fluid block arranged to be cooled by the cold side and to cool the fluid when the fluid passes through the fluid block and at least one heat transfer element arranged to transfer heat from the hot side.