ANÁLOGOS DE QUINAZOLINA COMO INIBIDORES DE TIROSINA-CINASES RECETORAS

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专利权人:

INC.;ARRAY BIOPHARMA

发明人:

QIAN ZHAO,ELI WALLACE,GEORGE TOPALOV,JOSEPH LYSSIKATOS,ALEXANDRE BUCKMELTER

申请号：

PT04780990

公开号：

PT1660090E

申请日:

2004.08.10

申请国别(地区):

PT

年份:

2013

代理人:

摘要：

This invention provides quinazoline analogs of Formula I: where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R3 groups. The invention also includes methods of using compounds of Formula I as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/