Kinazolinski analogi kot inhibitorji receptorjev tirozin kinaze

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专利权人:

INC.;ARRAY BIOPHARMA

发明人:

WALLACE ELI,TOPALOV GEORGE,LYSSIKATOS JOSEPH,BUCKMELTER ALEXANDRE,ZHAO QIAN,WALLACE Eli,TOPALOV George,LYSSIKATOS Joseph,BUCKMELTER Alexandre,ZHAO Qian

申请号：

SI200431985

公开号：

SI1660090T1

申请日:

2004.08.10

申请国别(地区):

SI

年份:

2013

代理人:

摘要：

This invention provides quinazoline analogs of Formula (I): where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R 3 groups. The invention also includes methods of using compounds of Formula (I) as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

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