Joseph Lyssikatos;George Topalov;Alexandre Buckmelter;Eli Wallace;Qian Zhao
发明人:
Eli Wallace,George Topalov,Joseph Lyssikatos,Alexandre Buckmelter,Qian Zhao
申请号：
US12249421
公开号：
US08278314B2
申请日:
2008.10.10
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention provides quinazoline analogs of Formula I:where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R3 groups. The invention also includes methods of using compounds of Formula I as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
