This invention provides a combined pharmaceutical composition and a combined use of agents for prophylaxis and/or treatment of dyslipidemia status such as hypercholesterolemia in mammals including human. The present invention is related to a pharmaceutical composition for prophylaxis and/or treatment of dyslipidemia and the likes containing (R)-2-[3-[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy]butyric acid, or a salt thereof, or a solvate thereof, and ω-3 fatty acid or a ester derivate thereof.本發明提供一種用以預防及/或治療包含人類之哺乳動物中如高LDL血症之異常血脂症狀態之組合醫藥組成物及藥劑之併用。本發明關於一種異常血脂症等之預防及/或治療用醫藥組成物，其含有(R)-2-[3-[[N-(苯并唑-2-基)-N-3-(4-甲氧基苯氧基)丙基]胺基甲基]苯氧基]丁酸或其鹽或者該等者之溶劑合物、及ω-3脂肪酸或其酯衍生物。
