Corey Anderson,Sara Sabina Hadida Ruah,Julian Marian Charles Golec,Beili Zhang,Benjamin Joseph Littler,Ali Keshavarz-Shokri,Tim Edward Alcacio,Daniel T. Belmont
申请号:
US16283904
公开号:
US20190276483A1
申请日:
2019.02.25
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention relates to prodrug compounds of formula I:wherein R2, R3, R5, R7 and X are as defined herein. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain. The compounds of formula I possess advantageous solubility and physicochemical properties.