Corey Anderson,Sara Sabina Hadida-Ruah,Julian Marian Charles Golec,Beili Zhang,Benjamin Joseph Littler,Ali Keshavarz-Shokri,Tim Edward Alcacio,Daniel T. Belmont
申请号:
US15260778
公开号:
US09828397B2
申请日:
2016.09.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to prodrug compounds of formula I:wherein R2, R3, R5, R7 and X are as defined herein. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain. The compounds of formula I possess advantageous solubility and physicochemical properties.