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AN ANTIBODY MEDICINAL PRODUCT
专利权人:
ЧУГАИ СЕЙЯКУ КАБУСИКИ КАЙСЯ (JP)
发明人:
САЭКИ Ацуси (JP),НИСИДЗАВА Сё (JP),САСАКИ Хитоси (JP),ИМАЙ Тифуми (JP),ИГАВА Томоюки (JP)
申请号:
RU2018141173
公开号:
RU2018141173A
申请日:
2017.04.27
申请国别(地区):
RU
年份:
2020
代理人:
摘要:
The present invention relates to a stable antibody-containing liquid preparation which rarely undergoes the formation of aggregates of Emicizumab (ACE910) that is a bispecific antibody having a function alternative to the function of FVIII. More specifically, the present invention relates to the aforementioned antibody-containing liquid preparation which contains 20 to 180 mg/mL of the aforementioned bispecific antibody, 10 to 40 mM of a histidine-aspartate buffer solution, 0.2 to 1 mg/mL of Poloxamer 188 and 100 to 300 mM of arginine and has a pH value of 4.5 to 6.5.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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