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PREPARATION CONTENANT UN ANTICORPS
专利权人:
CHUGAI SEIYAKU KABUSHIKI KAISHA
发明人:
SAEKI, ATSUSHI,NISHIZAWA, SHAW,SASAKI, HITOSHI,IMAI, CHIFUMI,IGAWA, TOMOYUKI
申请号:
CA3016301
公开号:
CA3016301A1
申请日:
2017.04.27
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to a stable antibody-containing liquid preparation which rarely undergoes the formation of aggregates of Emicizumab (ACE910) that is a bispecific antibody having a function alternative to the function of FVIII. More specifically, the present invention relates to the aforementioned antibody-containing liquid preparation which contains 20 to 180 mg/mL of the aforementioned bispecific antibody, 10 to 40 mM of a histidine-aspartate buffer solution, 0.2 to 1 mg/mL of Poloxamer 188 and 100 to 300 mM of arginine and has a pH value of 4.5 to 6.5.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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