COMPOSITIONS DE SONDE MOLECULAIRE D'IMAGERIE SPECIFIQUE DES MACROPHAGES CD206+ ET PROCEDES ASSOCIES, ET QUANTIFICATION NON INVASIVE DE L'INFILTRATION DES MACROPHAGES DE LA PAROI ARTERIELLE CHEZ L'HUMAIN
COPE, FREDERICK O.,RALPH, DAVID ALLEN,ABBRUZZESE, BONNIE CHANDLER
申请号:
CA3064277
公开号:
CA3064277A1
申请日:
2018.05.18
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Described herein are compositions and methods fordiagnosing, imaging, and quantifying non-calcified atherosclerotic plaque.Embodiments of compositions described herein comprise mannosylateddextran compounds along with other carbohydrate molecules comprising,for example, a diagnostic agent and a diagnostic moiety. The compoundsand methods embodied herein produce superior localization and resultsfor imaging, anatomically locating, and quantifying non-calcifiedatherosclerotic plaque.