JANG, DAE SIK,장대식,PARK, SANG SU,박상수,KIM, HAE MI,김해미,LEE, JA YEON,이자연,LEE, JIN SU,이진수
申请号：
KR1020170098111
公开号：
KR1018954300000B1
申请日:
2017.08.02
申请国别(地区):
KR
年份:
2018
代理人:
摘要：
The present invention relates to a method for separating fukinolic acid from a Petasites japonicus extract. According to the present invention, a large amount of high purity fukinolic acid can be obtained from the Petasites japonicus extract, and fukinolic acid can be used as a commercialized standard form. The method comprises the steps of: (a) adding water to Petasites japonicus leaves and performing extraction； (b) freeze-drying the extract； (c) adding ethanol to the extract and performing precipitation； (d) removing supernatant and freeze-drying the precipitate； (d) performing diaion column chromatography； (f) performing sephadex column chromatography； and (e) performing lichroprep column chromatography.본 발명은 머위 잎 추출물로부터 푸키놀릭산을 분리하는 방법에 관한 것이다. 본 발명에 따르면 머위 잎 추출물로부터 순도 높은 푸키놀릭산을 대량 수득할 수 있고, 이를 상용화된 표준폼으로 사용할 수 있다.
