Lentigen Technology, Inc.;The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人:
Rimas Orentas,Dina Schneider,Boro Dropulic,Dimiter S. Dimitrov,Zhongyu Zhu
申请号:
US15934770
公开号:
US10426797B2
申请日:
2018.03.23
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Chimeric antigen receptors containing CD33 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.