The U.S.A., as represented by the Secretary, Department of Health and Human Services;LentigenTechnology, Inc.
发明人:
Rimas J. Orentas,Dina Schneider,Boro Dropulic,Dimiter S. Dimitrov,Zhongyu Zhu
申请号:
US16773379
公开号:
US20200155661A1
申请日:
2020.01.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Chimeric antigen receptors (CARs) containing CD22 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the CARs are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making CAR T cells are also disclosed.